IndraLab

Statements

Methanol inhibits KCNH2. 2 / 2
| 2
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"Methanol, ethanol, DMSO, acetonitrile, PEG400, inhibited the hERG K + current in a concentration-dependent manner including almost complete reversibility of block (exception: PEG400)."
17590357
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"Considering that K + channel has relatively high selectivity for the permeating ion, K + rather than Na +, Ca 2+, and Cl -, the MeOH extract at relatively high concentrations of 100 and 300 microg/mL, could perturb the ion-selectivity of HERG channel by inducing non specific membrane permeabilization or membrane leakage."
19949665