IndraLab

Statements


8 1 | 2 1

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"These findings highlight the complexity of TRIM21 regulation and indicate that CSN6-CUL1 regulation is involved in TRIM21 ubiquitination."

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"First, we found that CSN6 associated with Myc, Fbxw7 and Cullin-1 in U2OS cells in vivo (XREF_FIG), suggesting that CSN6 interacts with SCF complex and may regulate it to stabilize Myc."

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"We found that both CSN6 and CSN5 associated with Cullin-1 and that CSN6 and CSN5 competed with each other for Cullin-1 binding in a dose dependent manner (XREF_FIG)."

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