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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP18 activates UBA7. 2 / 2

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"Subsequently, we also show that ISG15, but not USP18 and IL-6, induces UBA7, UBE2L6, and HERC5 genes via further downstream activation of STAT1."

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"These findings is consistent with previous studies in which all-trans-retinoic acid (RA) promotes the transcription of ISG15, USP18, and ISGylation activating enzyme UBE1L in RA sensitive but not resistant leukemia cells [XREF_BIBR]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...