IndraLab

Statements

USP50 activates WRN. 2 / 2
| 2
reach
"USP50 supports WRN:FEN1 at stalled replication forks, suppresses MUS81-dependent fork collapse and restricts double-strand DNA breaks at GC-rich sequences."
38260523
reach
"These data suggest that USP50 promotes the ability of WRN to associate with chromatin and with the 9-1-1.We were curious to test whether USP50 impacts WRN turnover and treated cells with the translation-inhibitor cycloheximide to observe WRN degradation rates."
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