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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

USP28 activates cell differentiation. 3 / 3

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"Usp28 deficiency promoted tumor cell differentiation accompanied by decreased proliferation, which suggests that USP28 acts similarly in intestinal homeostasis and colorectal cancer models."

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"Knockdown of USP28 directly increases the expression of differentiation genes but indirectly suppresses the expression of pluripotent molecules."

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"Knockdown of USP28 induces differentiation and suppresses self-renewal in CSCs derived from MMTV-Wnt1 mice."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

USP28 activates cell differentiation. 3 / 3

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