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ATXN3 increases the amount of BAX. 2 / 3

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"p53 activation mediates polyglutamine expanded ataxin-3 upregulation of Bax expression in cerebellar and pontine nuclei neurons."

21092747

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"In the present study, cellular and animal models of SCA3 were used to test the hypothesis that mutant polyglutamine ataxin-3 upregulates Bax expression of cerebellar and pontine nuclei neurons by augmenting transcriptional activity of p53."

21092747

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IndraLab

Statements

ATXN3 increases the amount of BAX. 2 / 3

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