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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

CFH activates USP1. 1 / 1

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"In agreement with polysomal analysis of USP1 mRNA translation regulation by hnRNP H/F or DHX36, silencing of either of these factors or treatment with cPDS reduced USP1 protein expression, providing further support for a RG4 dependent translational mechanism in which both hnRNP H/F and DHX36 cooperate to activate USP1 protein synthesis."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...