IndraLab

Statements



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"The antioxydant N-acetylcysteine can inhibit both ATPmediated caspase-1 activation and, interestingly, NLRP3 inflammation activation due to treatment with ionophores such as nigericin."

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"N-Acetylcysteine Inhibits Caspase-1 Activation In Cells Treated With Stone DAMPs."

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"Equally, administration of n-acetylcysteine to fasted WT mice prevented HFD dependent learning impairment and caspase-1 activation in the BLp."

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"In addition, N-acetylcysteine (NAC), a scavenger of reactive oxygen species (ROS),can effectively inhibit caspase-1 activation and the production of mature IL1-β ( Jabir et al., 2015 )."

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"N-acetylcysteine treatment at 0 and 24 hours after hypoxia-ischemia in lipopolysaccharide -exposed 8-day-old rats dramatically improved pathology scores and decreased caspase 1 and 3 compared with saline controls, while N-acetylcysteine delayed until 2 hours and 24 hours after hypoxia-ischemia had no beneficial effect."