IndraLab

Statements

Cyclosporin A inhibits KCNH2. 3 / 3
| 3
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"CsA blocked the HERG channels predominantly in the open and inactivated states rather than in the closed state."
22128262
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"Pretreatment with cypermethrine, a calcineurin inhibitor, had no effect on the CsA induced inhibition of the HERG channel."
22128262
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"CsA inhibited the HERG channel in a concentration dependent manner, with an IC (50) value and a Hill coefficient of 3.17 microM and 0.89, respectively."
22128262