IndraLab

Statements

USP36 deubiquitinates YAP1. 4 / 4
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"USP36 interacts with YAP and inhibits YAP polyubiquitination and breakdown, which further promotes esophageal cancer progression (Fig. 6G)."
36470870
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"USP36 could associate with YAP and deubiquitinate YAP protein, which further leads to enhanced Hippo/YAP activity."
36470870
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"These findings indicate that USP36 interacts with YAP and plays a role in deubiquitinating YAP, thereby positively influencing Hippo/YAP signaling activity."
38785979
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"The ubiquitination assay indicated that USP36 depletion could significantly increase the total YAP ubiquitination level, but USP36 overexpression could decrease the total YAP ubiquitination level (Fig. 6A, B)."
36470870