IndraLab

Statements

USP1 inhibits cisplatin. 6 / 6
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"This view has gained recent support with the finding that USP1 inhibition may contribute to revert cisplatin resistance in an in vitro model of non small cell lung cancer (NSCLC)."
23937906
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"In addition, USP1 inhibition enhances sensitivity of PDAC cells to cisplatin and shows a synergistic antitumor effect."
39814232
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"Another USP1/UAF1 inhibitor, ML323, has also been developed to enhance the cytotoxicity of cisplatin in NSCLC and osteosarcoma cells [191]."
37728310
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"The cell viability assay results showed that the depletion of USP1 and USP28 increased the cytotoxicity of cisplatin and sensitized the cisplatin-resistance in HeLa cells (Fig. 1A)."
38498222
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"These findings are consistent with those of Chen et al. [XREF_BIBR], and suggest that USP1 inhibition may contribute to revert cisplatin resistance in some preclinical models of NSCLC."
23937906
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"The pharmacological inhibition of USP1 synergistically enhances the efficiency of cisplatin in PDAC cells."
39814232