IndraLab

Statements

PRPF8 binds EFTUD2. 20 / 20
9 | 3 8
biogrid
No evidence text available
9774689
biogrid
No evidence text available
27173435
sparser
"To determine whether the interactions between R2TP and PRPF8 or EFTUD2 occur at an early cytoplasmic stage, we implemented a corecruitment assay using a fusion of RPAP3 with a fragment of p54, which targets the fusion protein to cytoplasmic P-bodies ( xref )."
28515276
biogrid
No evidence text available
25263594
sparser
"We also identified several U5 chaperones such as AAR2, ZNHIT2, RUVBL1, RUVBL2, and ECD and a putative chaperone EAPP that has been shown to interact with U5 proteins PRPF8 and EFTUD2 xref , xref , xref ."
34131137
sparser
"The HSP90/R2TP machinery binds unassembled cytoplasmic forms of PRPF8 and EFTUD2."
28515276
reach
"An intermediate complex is formed with the recruitment of PRPF8 and EFTUD2 to the R2TP and HSP90 complex along with AAR2, ZNHIT2, and other assembly factors."
28884116
biogrid
No evidence text available
22939629
sparser
"SNRNP200 is a large nuclear protein of 200 kDa, which interacts extensively with U5-specific proteins EFTUD2 (hSnu114) and Prpf8."
27302685
biogrid
No evidence text available
26344197
sparser
"This indicated that EFTUD2 interacts with R2TP in the cytoplasm independently of PRPF8."
28515276
biogrid
No evidence text available
16723661
biogrid
No evidence text available
16723661
biogrid
No evidence text available
9774689
sparser
"Both domains make specific contacts with U5 subcomplexes where Hom3 primarily interacts with PRPF8 and EFTUD2 proteins that form a subcomplex early during biogenesis xref and Hom2 mediates interaction with the mature U5 particle."
34131137
reach
"To determine whether the interactions between R2TP and PRPF8 or EFTUD2 occur at an early cytoplasmic stage, we implemented a corecruitment assay using a fusion of RPAP3 with a fragment of p54, which targets the fusion protein to cytoplasmic P-bodies."
28515276
biogrid
No evidence text available
17317632
sparser
"Collectively, our data confirm that interactions of the R2TP complex with PRPF8 and EFTUD2 occur early on in the cytoplasm and are independent of each other."
28515276
sparser
"Given that this stem structure appears to associate with the N-terminal region of Prp8 and Snu114 in the yeast spliceosomal complex ( xref ), 11 Ψ may contribute to the stabilization of interactions of the human complex with p220 and SNU114."
26673725
reach
"The proteomic analysis of the GFP IPs showed a strong association of PRPF8-LAP with its partners EFTUD2 and SNRNP200, and conversely, GFP-EFTUD2 strongly bound PRPF8 and SNRNP200."
28515276