IndraLab

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KCNMA1 inhibits FMR1. 1 / 1
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reach
"Unfortunately, startle habituation is not well studied in humans with FXS or Fmr1 ko mice, however, the allosteric BK channel activator BMS-204352 was shown to reverse behavioural and cellular FXS symptoms in Fmr1 ko mice, highlighting the potential of studying sensory filtering mechanisms in animal models for developing pharmaceutical treatments."