IndraLab
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"These results imply that miR-145-3p regulates COX1 and COX2 genes, which possibly associates with mitochondrial activity.We subsequently knocked down MYBL1 and found that deficiency of MYBL1 in proliferating MuSCs decreased the expression of VCPIP1, Vexin, and COX1, while that of COX2 was increased (Figure 6F), which exactly mimics the inhibitory effect of ectopic miR-145-3p on these genes."