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USP53 inhibits cell population proliferation. 9 / 9
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"BrdU cell proliferation assay was also used to test the proliferative ability of cells, and the proliferation of USP53 overexpression cells was inhibited compared with control (Figure 2G,H).3.3 Knockdown USP53 promotes the growth and proliferation of ccRCC."
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"Then, we performed immunohistochemical staining on the tissues of patients with renal clear cell carcinoma and found that the expression of USP53 in tumor tissues was significantly lower than paracancerous tissues (Figure 1F).3.2 Overexpression USP53 inhibits the growth and proliferation of ccRCC."
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"In summary, our data showed that USP53 inhibits ccRCC proliferation and metastasis through NF‐κB pathway inactivation."
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"Our data indicate that USP53 inhibits cancer cell proliferation and migration."
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"Through CCK‐8 assay, we found that overexpression of USP53 in Caki‐1 and 786‐O cells significantly inhibited cell proliferation (Figure 2C,D)."
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"The proliferation and metastasis of ccRCC were significantly inhibited by USP53 in vitro."
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"Functionally, ectopic USP53 expression reduced cell proliferation and cell migration in vitro and vice versa."
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"USP53 suppresses the proliferation and growth of ESCA cells in vitro and in vivo, whereas its knockdown exerts opposite effects."
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"Furthermore, the ectopic expression of USP53 inhibited the proliferation, migration and invasion, and induced the apoptosis of HCC cells."
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