IndraLab

Statements

COPS5 activates ERN1. 2 / 2

| 2

reach

"Upon ER stress, JAB1 dissociates from IRE1alpha, allowing IRE1alpha to splice XBP1 mRNA into XBP1s, suggesting that JAB1 inhibits IRE1alpha through its binding 55."

28550308

➶

reach

"Nevertheless, our data suggested the possibility that JAB1-IRE1alpha binding was increased to suppress UPR when the stimulus was weak, while JAB1 rapidly dissociated from IRE1alpha to allow IRE1alpha [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

15234121

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

COPS5 activates ERN1. 2 / 2

INDRA sources:

Databases

Reading