IndraLab

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USP8 activates Death. 2 / 2

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reach

"Silencing or pharmacological inhibition of USP8 deubiquitinase, relevant in particular to the stability of RTKs such as EGFR and MET, was shown to induce death of gefitinib resistant NSCLC cells in vitro and in vivo [XREF_BIBR]."

24722523

➶

reach

"USP8 siRNAs reduced viability and increased death in cSCC lines but had little effect in normal skin cells (XREF_FIG a)."

31705877

INDRA sources:

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IndraLab

Statements

USP8 activates Death. 2 / 2

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