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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

EIF4G inhibits USP10. 1 / 1

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"Our previous study showed that EIF4G1 combined with USP10 in the lung cancer cell line A549, as determined by co-immunoprecipitation analysis, so we assume that EIF4G1 can inhibit the USP10 mediated stabilization of p53 by binding to USP10, leading to the inhibition of p53 functions in cancer cells."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...