IndraLab

Statements


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"In Drosophila, loss of PRPF8 decreases cell proliferation, increases cell death and modulates cell differentiation and polarity, and PRPF8-mediated hyperplastic growth is induced by different oncogenes ."

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"Knockdown of c-MYC attenuated cell death caused by depletion of PRPF8 or SF3B1 in SCCRDEBMet cells and depletion of PRPF8 in SCCRDEB4 cells."

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"Knockdown of SF3B1, PRPF8, UBL5 and USP39 increased cell death in all cSCC cell lines."