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USP20 deubiquitinates HIF1. 2 / 2

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"VDU2 can interact with HIF-1α, a tumor suppressor, to deubiquitinate and stabilize HIF-1α (Li et al., 2005)."

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"VDU2 (pVHL-interacting deubiquitinating enzyme 2) interacts with and deubiquitinates HIF-1α and is itself ubiquitinated in a VHL-E3 ligase-dependent (but oxygen-independent) manner [101,102] ."

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USP20 deubiquitinates HIF1. 2 / 2

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