Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Superoxide increases the amount of ATXN3. 1 / 1

| 1

➶

reach

"ATXN3 interacts with and stabilizes the forkhead box O (FOXO) transcription factor FOXO4, and upon oxidative stress they both translocate to the nucleus and activate manganese superoxide dismutase (SOD2) transcription which in turn protects cells from oxidative damage."

22133674

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...