IndraLab

Statements

Cysteine inhibits NLRP3. 3 / 3
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"Reduction of intracellular O 2 *- and H 2 O 2 levels prevented Hcys induced NLRP3 inflammasome formation in podocytes."
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"It was found that ebselen, a putative ONOO - scavenger, failed to decrease formation and activation of NLRP3 inflammasomes in podocytes treated with Hcys, suggesting ONOO - may not play a critical redox role in this particular pathological process in podocytes."
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"The * OH scavenger TMTU did not significantly inhibit any measure of Hcys induced NLRP3 inflammasome formation or activation, suggesting that in comparison to O 2 *- and H 2 O 2, * OH does not play a crucial role to inflammasome stimulation."
24140862