IndraLab

Statements

Antagonist inhibits IRF3. 2 / 2
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"Lui et al. reported that the MERS-CoV M glycoprotein is an IFN antagonist because it specifically inhibited IRF3 activation but not NF-κB signaling (41)."
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"Here we identify TRIM56 as a cellular protein associated with the N-terminal protease (N(pro)) of bovine viral diarrhea virus (BVDV), a pestiviral interferon antagonist which degrades interferon regulatory factor 3 (IRF3) through the proteasome."
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