IndraLab

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"Notably, we show that released, cytosolic HtrA2 decreases UCH-L1 protein level and its hydrolase activity through HtrA2 mediated cleavage of UCH-L1 under apoptotic conditions."

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"For example, Ubiquitin carboxy-terminal hydrolase L1 antisense RNA 1 (UCHL1-AS1) interacts with polysomes and thus promotes the translation of UCHL1 mRNA."