IndraLab

Statements

COPS5 activates Neoplasm Invasiveness. 15 / 15
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"CSN5 promotes the invasion and metastasis of pancreatic cancer by stabilization of FOXM1."
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"Further, silencing of CSN5 expression markedly inhibited PC invasion and metastasis in vitro and in vivo, accompanied by decreased MMP2 expression."
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"COPS5 overexpression promoted, whereas METTL3 knockdown markedly inhibited MG63 and U2OS cells viability ( Fig. 7 C), migration ( Fig. 7 D), and invasion ( Fig. 7 E); COPS5 overexpression also partial[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Overexpression of JAB1 promoted the proliferation, migration, and invasion of ESCC cells, and was significantly associated with poor prognosis of ESCC patients."
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"Taken together, the results indicate that CSN5 can contribute to PC invasion and metastasis through activation of FOXM1 and MMP2 axis."
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"We found that COPS5 knockdown repressed proliferation, migration, and invasion and facilitated apoptosis of OS cells."
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"In present study, our data indicated that knockdown of CSN5 could decrease the invasion and metastasis of HCC in vitro and in vivo ."
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"Strikingly, the knockdown of COPS5 significantly decreased both the migratory ability and invasiveness of both A549 and Panc-1 cell lines, in concert with the reduction of SNAIL and its downstream target protein, Vimentin [XREF_BIBR]."
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"Zhong G, Li H, Shan T, Zhang N. CSN5 silencing inhibits invasion and arrests cell cycle progression in human colorectal cancer SW480 and LS174T cells in vitro."
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"Using an in vitro invasion assay, we found that knockdown of either Stat3 or Jab1 significantly decreased NPC cell invasion (XREF_FIG)."
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"Recently, CSN5-mediated stabilization of ZEB1 promotes renal cell carcinoma migration and invasion by inducing epithelial-mesenchymal transition [ 11 ]."
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"CSN5 silencing inhibits invasion and arrests cell cycle progression in human colorectal cancer SW480 and LS174T cells in vitro."
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"In addition, CSN5, through stabilization of FOXM1, promotes invasion and metastasis in pancreatic cancer [ 28 ]."
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"CSN5 promotes the invasion and metastasis of pancreatic cancer by stabilization of FOXM1 [37]."
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"As shown in Fig. 3 G and H, the results shown that the knockdown of CSN5 dramatically decreased the migration and invasion abilities of ACHN cells, whereas the upregulation of ZEB1 rescued the decreas[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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