IndraLab

Statements

COPS5 activates Neoplasm Invasiveness. 7 / 7
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"Taken together, the results indicate that CSN5 can contribute to PC invasion and metastasis through activation of FOXM1 and MMP2 axis."
30352219
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"CSN5 promotes the invasion and metastasis of pancreatic cancer by stabilization of FOXM1."
30352219
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"Using an in vitro invasion assay, we found that knockdown of either Stat3 or Jab1 significantly decreased NPC cell invasion (XREF_FIG)."
27524414
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"Further, silencing of CSN5 expression markedly inhibited PC invasion and metastasis in vitro and in vivo, accompanied by decreased MMP2 expression."
30352219
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"Overexpression of JAB1 promoted the proliferation, migration, and invasion of ESCC cells, and was significantly associated with poor prognosis of ESCC patients."
32064781
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"CSN5 silencing inhibits invasion and arrests cell cycle progression in human colorectal cancer SW480 and LS174T cells in vitro."
26045788
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"Strikingly, the knockdown of COPS5 significantly decreased both the migratory ability and invasiveness of both A549 and Panc-1 cell lines, in concert with the reduction of SNAIL and its downstream target protein, Vimentin [XREF_BIBR]."
29755680