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Haloperidol inhibits FOS. 8 / 8
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"Consistently, haloperidol-induced VCMs and decrease in the number of c-Fos + /ppENK + iMSNs were also mitigated by intrastriatal injection of CGS 21680A."
36760795
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"However, haloperidol induced c-Fos activation in the striatum and catalepsy were significantly attenuated in TAAR1-KO mice (Espinoza et al., 2011)."
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"Muscarinic receptor antagonists suppressed haloperidol induced c-fos expression throughout the shell and in the mid-level of the core of the nucleus accumbens while A (2) and H (3) receptor antagonists did not.We found that the muscarinic and H (3) receptor antagonists suppress the induction of c-fos by haloperidol in the dorsolateral aspect of the striatum, an area implicated in the development of extrapyramidal motor symptoms following chronic haloperidol treatment."
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"However, further studies investigating the direct involvement of A2AR-Gs cascade in the induction of iMSN activity are required for understanding the precise therapeutic mechanisms of A2AR stimulation in haloperidol-induced VCMs.Consistent with the hypothesis that A2AR stimulation recovers the neural activity of iMSNs in haloperidol-treated mice, we showed that repeated administration of haloperidol decreased the number of c-Fos /ppENK iMSNs, which was successfully increased by intrastriatal activation of A2AR."
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"Haloperidol induced c-fos was augmented in the striatum and pituitary, but reduced in the frontal cortex by chronic lithium treatment."
9165496
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"In METH-treated group, haloperidol significantly suppressed the METH-induced increase in the number of c-Fos–positive cell in the infralimbic mPFC, but further increased the c-Fos-positive cell number[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"A 21-day treatment with haloperidol increased the number of vacuous chewing movements (VCMs) and decreased the number of c-Fos + /ppENK + iMSNs in the dorsal striatum."
36760795
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"Globus pallidus lesions inhibit the induction of c-Fos by haloperidol in the basal ganglia output nuclei in rats."
9696058