IndraLab

Statements

Calcium_channels inhibits CACNA1A. 6 / 6
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"Using calcium indicator dyes we identified a source of calcium for asynchronous release that, under conditions of P/Q type calcium channel inhibition, originated in the axons and branch points and appeared to propagate into the synaptic boutons."
24368731
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"In Timothy syndrome, a “gain of function” mutation in the L-type calcium channel leads to reduced voltage dependent calcium channel inactivation [ xref ]."
26925288
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"These data suggest that, in addition to an increase in current density, dystrophin-deficiency also generated a reduction in voltage-dependent calcium channel inactivation."
24337461
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"As for facilitation, calcium-dependent STD could implicate calcium binding proteins, that could in turn regulate various processes such as voltage-dependent calcium channel inactivation or recovery of the immediately releasable vesicle pool [ xref , xref , xref , xref ]."
28820903
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"MORs can hyperpolarize some VTA dopamine neurons via increasing potassium conductance or exciting them via P/Q type calcium channel (Cav2.1) inhibition ( xref , xref )."
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"Thus, since eugenol was able to induce a profound vasodilatory response that was ¹84% of the noradrenaline-induced tonic increase in perfusion pressure at the highest dose used (20 ·mol), it would appear to be exerting its vascular relaxant effects predominantly via a mechanism(s) independent of voltage-dependent calcium channel inhibition."
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