IndraLab

Statements


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"In turn, CD164 functionally interacts with CXCR4, thus regulating CXCR4 activation and CXCL12-dependent motility of EWS cells."

sparser
"We report here that CD164 is associated with CXCR4 in C2C12 myoblasts."

reach
"Moreover, it was reported that sialomucin endolyn (CD164), an adhesion receptor that regulates the adhesion of CD34 + cells to BM stroma and their recruitment into the cycle, associates with CXCR4, an interaction that follows the association of CXCR4 with the integrins VLA-4 and VLA-5 [XREF_BIBR]."

sparser
"Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 Modulates Aggressiveness of Ewing Sarcoma by Regulating the CD164-CXCR4 Axis."

sparser
"The knockdown of CD164 expression was associated with decreased chemokine receptor CXCR4 expression HCT116 cell surface and immunoprecipitation studies showed that CD164 formed complexes with CXCR4."

sparser
"To confirm that CD164 and CXCR4 indeed interacts at the plasma membrane, we repeated colocalization experiments supplementing CXCL12 with the general endocytosis inhibitor dynasore, a GTPase inhibitor that blocks dynamin activity, thus affecting both clathrin-dependent and -independent endocytic pathways ( xref )."

reach
"Taken together these data support a role of IGF2BP3 in regulating the CD164 and CXCR4 complex and demonstrate the evidence of an IGF3BP3-CD164-CXCR4 oncogenic axis critical for EWS progression."

reach
"The knockdown of CD164 expression was associated with decreased chemokine receptor CXCR4 expression HCT116 cell surface and immunoprecipitation studies showed that CD164 formed complexes with CXCR4."

reach
"In turn, CD164 functionally interacts with CXCR4, thus regulating CXCR4 activation and CXCL12 dependent motility of EWS cells."

sparser
"CD164 associates with CXCR4 and cooperates with it in promoting CXCL12-mediated cell migration ( xref )."

sparser
"They further showed that CD164 associates with CXCR4 in the presence of SDF1α and fibronectin, followed by the association of CXCR4 with the integrins VLA-4 and VLA-5."

reach
"Here, we provide evidence that the sialomucin endolyn (CD164), an adhesion receptor that regulates the adhesion of CD34+ cells to bone marrow stroma and the recruitment of CD34+ CD38 (lo/-) cells into cycle, associates with CXCR4."

reach
"Chi‐square tests and correlation analysis (Pearson and Spearman) were performed to analyze the associations between CD164 and CXCR4."

sparser
"On presentation of CXCL12 on fibronectin, CD164 associates with CXCR4, an interaction that temporally follows the association of CXCR4 with the integrins VLA-4 and VLA-5."