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Rpr activates KCNH2. 1 / 1
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"The first hERG1 activator to be discovered, RPR260243 ((3R,4 R)-4-[3-(6-methoxyquinolin-4-yl)-3-oxo-propyl]-1-[3-(2,3,5-trifluorophenyl)-prop-2-ynyl]-piperidine-3-carboxylic acid) (RPR) induces a pronounced, voltage dependent slowing of hERG1 deactivation."