IndraLab

Statements

AGL11 activates HCN4. 2 / 2
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reach
"These results are in agreement with the previous findings that the main sites (Y531 and Y554) that mediate STK enhancement of HCN4 are located in the C-linker, excluding the CNBD and the distal C-terminal region."
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reach
"Increased STK activity increases HCN4 activity associated with an enhanced surface expression and tyrosine phosphorylation of the channel protein, whereas inhibited STK activity by PP2 decreases HCN4 channel conductance associated with a decreased tyrosine phosphorylation of the channel proteins."
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