IndraLab

Statements

OTUD1 deubiquitinates SMAD7. 5 / 5
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"Breast cancer metastasis suppressor OTUD1 deubiquitinates SMAD7"
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"OTUD1 deubiquitinates SMAD7 and sustains SMAD7 stability."
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"Further investigation reveals that OTUD1 directly deubiquitinates the TGF-beta pathway inhibitor SMAD7 and prevents its degradation."
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"To demonstrate that OTUD1 can directly deubiquitinate SMAD7, we performed in vitro deubiquitination assays."
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"This confirms that OTUD1 deubiquitinates SMAD7 in vitro."
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