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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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OTUD1 deubiquitinates SMAD7. 5 / 5

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"Breast cancer metastasis suppressor OTUD1 deubiquitinates SMAD7"

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"OTUD1 deubiquitinates SMAD7 and sustains SMAD7 stability."

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"Further investigation reveals that OTUD1 directly deubiquitinates the TGF-beta pathway inhibitor SMAD7 and prevents its degradation."

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"To demonstrate that OTUD1 can directly deubiquitinate SMAD7, we performed in vitro deubiquitination assays."

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"This confirms that OTUD1 deubiquitinates SMAD7 in vitro."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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OTUD1 deubiquitinates SMAD7. 5 / 5

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