IndraLab

Statements

MiR-369-3p decreases the amount of BRCC3. 3 / 3
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"The increase in miR-369-3p was able to significantly reduce the expression of the BRCC3 gene and protein."
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"We demonstrated that under inflammatory conditions, miR-369-3p is able to decrease the expression of Brcc3 in macrophages, modulating the deubiquitination of NLRP3, and hence the assembly and activation of the complex."
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"Western blot analysis confirmed that miR-369-3p was able to reduce BRCC3 protein expression in unstimulated cells and also after inflammasome-activating stimulations."
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