IndraLab

Statements


OGT binds HCFC1 and BAP1. 2 / 2
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"The fact that HCF-1 acts as an important modulator of cellular circadian rhythm [XREF_BIBR] raises the possibility that the OGT, HCF-1, and BAP1 complex interacts with the BMAL1, CLOCK, and PER complex to modulate circadian rhythm."

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"Within the BAP1/HCF-1/OGT complex, HCF1 is modified by O-GlcNacylation, the addition of single O-linked N-acetylglucosamine moiety to specific serine or threonine residues (50,51)."