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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

HSP90beta activates KCNQ4. 2 / 2

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"While overexpression of HSP90beta promotes KCNQ4 biogenesis, overexpression of HSP90alpha facilitates ubiquitin dependent degradation of the channel."

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"In addition, HSP90beta increased the number of active WT KCNQ4 channels at the cell surface, and slightly that of WT and L274H mixed channels; the number of active WT and W276S mixed channels was not improved."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...