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Mitoxantrone binds USP15. 2 / 2

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"Moreover, we report that USP15 is weakly inhibited by the antineoplastic agent mitoxantrone in vitro A USP15 and mitoxantrone complex structure disclosed that the anthracenedione interacts with the S1 ' binding site."

30228188

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"Crystal structure analysis by Ward et al. highlighted minute differences between the paralogs and noted that mitoxantrone binds and partially inhibits USP15, similar to USP11."

31481479

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IndraLab

Statements

Mitoxantrone binds USP15. 2 / 2

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