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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

NFkappaB activates COPS5. 2 / 2

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"Expression of CSN5 is induced by NF-kappaB which is activated by proinflammatory cytokine TNF-alpha [ 18,30 ] ."

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"Our findings suggest that defective NF-kappaB activation may underlie increased apoptosis of both DN and DP cells in CSN5 and JAB1 del and del mice, as both subsets display a major reversion of the stoichiometric ratio of anti- vs. proapoptotic Bcl-2 family members."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...