IndraLab

Statements

OTUB1 binds OTU. 8 / 8
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"The tumour stem cell molecules CD44 [91,92,93] and OTU deubiquitinase ubiquitin aldehyde binding 1 (OTUB1) [94] were beneficial to the stability of SLC7A11 on the cell membrane, and inhibited the proteasomal degradation of SLC7A11."
35804831
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"For instance, USP9X, ubiquitin-specific peptidase 47 (USP47), and OTU deubiquitinase ubiquitin aldehyde binding 1 (OTUB1) directly deubiquitinate YAP [33–35]."
37743467
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"Recent MS studies have shown that OTU deubiquitinase ubiquitin aldehyde binding 1 (OTUB1), a deubiquitinating enzyme of the OTU family, is enriched together with alpha-synuclein in LBs from individuals with PD and is also present in amyloid plaques associated with Alzheimer 's disease."
32005664
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"The ovarian tumor domain (OTU) deubiquitinylating cysteine proteases OTU ubiquitin aldehyde binding 1 (OTUB1) and OTUB2 are representative members of the OTU subfamily of deubiquitinylases."
32265297
sparser
"The clones in OTU1–OTU8, OTU13–OTU14, and OTU9–OTU12 and OTU15–OTU30 belonged to the classes Betaproteobacteria , Gammaproteobacteria , and Alphaproteobacteria , respectively ( xref )."
32713897
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"Therefore, unraveling the molecular mechanisms of GBM pathogenesis is urgently needed.The OTU structural domain ubiquitin aldehyde binding 1 (OTUB1) belongs to the ovarian cancer protease family, regulating ubiquitination and controlling the stability and function of proteins."
39006090
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"Using functional ubiquitination and deubiquitination assays, we show that the ovarian tumor (OTU) family deubiquitinase ubiquitin aldehyde binding 1 (OTUB1) inhibits MSH2 ubiquitination by blocking the E2 ligase ubiquitin transfer activity."
33640455
sparser
"Seven OTUs (OTU1–OTU7) were identified as members of Caballeronia by a BLAST search."
35965097