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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

COPS5 activates HTR6. 2 / 2

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"Moreover, the knockdown of Jab1 attenuated 5-HT 6 R agonist induced-Runx2 suppression as well as osteoblast differentiation as evidenced by ALP staining (XREF_FIG) and activity (F) and differentiation markers, ALP, OCN, and bone sialoprotein (BSP) (XREF_FIG)."

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"Our previous studies identified 5-HT 6 R associated partners such as Fyn, Jab1, and MAP1B which activate 5-HT 6 R function [XREF_BIBR XREF_BIBR XREF_BIBR], which are implicated in cognition, neurodevelopment, and neurodegeneration [XREF_BIBR XREF_BIBR XREF_BIBR XREF_BIBR XREF_BIBR]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...