IndraLab

Statements


USP25 inhibits CD274. 5 / 5
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"Overexpression of USP21 significantly increased PD-L1 abundance while its knockdown induced PD-L1 degradation."

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"This study reveals the mechanism of USP21-mediated PD-L1 degradation, and suggests that USP21 might be a potential target for the treatment of lung cancer."

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"The overexpression of USP21 significantly increases PD-L1 abundance, whereas its knockdown induces PD-L1 degradation [76]."

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"The resultant downregulation of USP21 as a deubiquitinating enzyme enhances PDL-1 degradation."

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"Increased USP21 elevated PD-L1 abundance, whereas depletion of USP21 promoted PD-L1 degradation."