IndraLab

Statements

USP4 inhibits Fibrosis. 4 / 4
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"In conclusion , USP4 was significantly elevated in autoimmune hepatitis mice and Vialinin A reduced USP4 level and attenuate inflammation and fibrosis in the liver ."
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"Researchers discovered that deubiquitinating USP4 (Ubiquitin-specific protease 4) keeps ACE2 stable, which in turn prevents EMT and fibrosis in LUAD."
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"USP4 deubiquitination maintains ACE2 stability and thus inhibits EMT and fibrosis in LUAD."
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"The intervention using Vialinin A and liver X receptor α (LXRα)-induced cannabinoid receptor 2 (CB2) has been found to reduce the level of USP4, leading to alleviate inflammation and fibrosis in the liver (74)."
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