IndraLab

Statements

USP48 deubiquitinates RELA. 4 / 4
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"As p65 is also a direct interactor and target of USP48 [17], the CSN complex promotes USP48-mediated deubiquitination of p65 and its stabilization on chromatin."
36077078
ubibrowser
"Catalytic domain of deubiquitinylase <span class="match term0">USP48</span> directs interaction with Rel homology domain of nuclear factor kappaB transcription factor <span class="match term1">RelA</span>"
30628021
reach
"USP48 interacts with the transcription factor NF-kappaB, deubiquitinates NF-kappaB subunit p65 and promotes its stability and activation, and up-regulates NF-kappaB target genes known to inhibit synaptogenesis."
37781625
reach
"USP48 deubiquitinates p65 and promotes its activation."
37781625