Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP18 inhibits IKBKB. 3 / 3

| 2 1

➶

sparser

"We found that the activation of NF-κB by MyD88, TRAF2, TRAF6, TAK1-TAB1, IKKα and IKKβ was markedly inhibited by USP18 ( xref )."

26240016

➶

reach

"They show that three USPs -- USP14, USP18, and USP22 -- fulfilled these criteria, but focused on USP14, as USP18 and USP22 could also inhibit IKKbeta activation directly in the absence of NLRC5."

26620908

➶

reach

"Importantly, we observed that USP18 and USP22, but not USP14, may directly inhibit IKK-beta activation through an NLRC5 independent mechanism."

26620909

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...