IndraLab

Statements


Mdb1 decreases the amount of KCNA2. 3 / 3
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"Mechanistically, MDB1 represses Oprm1 and Kcna2 gene expression by recruiting DNA methyltransferase DNMT3a into these two gene promoters in the DRG neurons."

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"We have also provided the evidence that MDB1 represses Oprm1 and Kcna2 gene expression by recruiting DNA methyltransferase DNMT3a into these two gene promoters in the DRG neurons."

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"Mechanistically, MDB1 represses the mu-opioid receptor gene Oprm1 and Kcna2 gene expression that encodes the potassium channel Kv1.2 protein by recruiting DNA methyltransferase DNMT3a into these two gene promoters in the DRG neurons."