IndraLab

Statements

ATXN3 deubiquitinates TP53. 3 / 4
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reach
"To determine whether ATX-3 can deubiquitinate p53 directly in vitro, we performed in vitro deubiquitination assays."
27851749
reach
"Thus, ATX-3 deubiquitinates and stabilizes p53 (XREF_FIG), which is an essential step for p53 function in cell cycle arrest and apoptosis (XREF_FIG)."
27851749
reach
"Interestingly, polyQ expansion in Ataxin-3 increases the interaction and deubiquitination of p53, which is upregulated."
30355526