IndraLab

Statements

MBNL1-AS1 inhibits KCNMA1. 4 / 4
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"MBNL1-AS1 targeted and negatively regulated KCNMA1."
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"We proved that KCNMA1 was negatively regulated by MBNL1-AS1, indicating that the role of MBNL1-AS1 in the protection of skeletal muscle cells against I/R injury might be associated with KCNMA1."
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"The results showed that MBNL1-AS1 was overexpressed in skeletal muscle cells in mice, while KCNMA1, which was enriched in the cGMP-PKG signaling pathway, was negatively regulated by MBNL1-AS1."
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"These results indicated that the KCNMA1 and cGMP-PKG pathways might be negatively regulated by MBNL1-AS1, while the overexpression of KCNMA1 could increase the expression of cGMP-PKG pathway related proteins suppressed by the overexpression of MBNL1-AS1."
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