IndraLab

Statements

STUB1 ubiquitinates KCNH2. 3 / 3
| 2 1
reach
"The documented CHIP dependent polyubiquitination of hERG, regardless of whether structural destabilization was attained by missense mutations or extracellular and intracellular K + depletion, suggests that the conformational defect recognized by the QC converges onto to the cytosolic domains."
24152733
reach
"The CHIP ablation effect could be attributed to CHIP dependent ubiquitination of hERG, since siCHIP reduced ouabain induced polyubiquitination of wt-hERG (XREF_FIG, lanes 3 and 6, and Supplemental Figure S5D)."
24152733
sparser
"The CHIP ablation effect could be attributed to CHIP-dependent ubiquitination of hERG, since siCHIP reduced ouabain-induced polyubiquitination of wt-hERG ( xref , lanes 3 and 6, and Supplemental Figure S5D)."
24152733