IndraLab

Statements

MiR-1180 inhibits OTUD7B. 2 / 2
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"Moreover, we reveal that the miR-1180 directly targets two negative regulators of the nuclear factor (NF)-kappaB signaling pathway (OTUD7B and TNIP2) XREF_BIBR XREF_BIBR XREF_BIBR, as well as the pro apoptotic Bcl-2 associated death promoter (BAD) protein, via post-transcriptional downregulation."
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"In summary, the present study demonstrates that the upregulation of miR-1180 contributes to the proliferation and cisplatin-resistance of HCC cells both in vitro and in vivo, by targeting and suppressing OTUD7B, TNIP2 and BAD."
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