IndraLab

Statements

SLC2A1 binds IGF1R. 6 / 6
| 2 4
sparser
"In Panel C, it can be seen that LRP1, together with GIPC (GAIP-interacting protein, C terminus), mediate the molecular interaction between IGF1-R and GLUT1, with GLUT1 being retained inside the cell."
29914093
sparser
"It has been reported that in astrocytes, LRP1 together with the scaffolding protein GIPC (GAIP-interacting protein, C terminus) mediate the molecular interaction between insulin-like growth factor 1 receptor (IGF1-R) and GLUT1."
29914093
sparser
"Expression of IGF-1R and GLUT1 were associated with poor overall survival in multivariate analysis, and therefore appear to be possible interesting biomarkers of radiation resistance."
28716107
sparser
"Expression of IGF-1R and GLUT1 could be associated with poor prognosis, and therefore appear to be possible interesting biomarkers of radiation resistance."
28716107
reach
"Regulated translocation of GluT1 to the cell membrane by IGF-IR involves an intricate repertoire of protein protein interactions amenable to drug modulation, particularly by interfering with IGF-IR and GluT1 interactions."
28859884
reach
"Analysis of underlying mechanisms indicated that IGF-IR interacts with glucose transporter 1 (GLUT1), the main facilitative glucose transporter in astrocytes, through a mechanism involving interactions with the scaffolding protein GIPC and the multicargo transporter LRP1 to retain GLUT1 inside the cell."
27462832