IndraLab

Statements

OTUD7B deubiquitinates SQSTM1. 8 / 8
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"OTUD7B/Cezanne (OTU deubiquitinase 7B) acts as a negative regulator of antiviral immunity by deubiquitinates SQSTM1/p62 and promotes IRF3 degradation [232]."
36653801
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"OTUD7B/Cezanne (OTU deubiquitinase 7B) acts as a negative regulator of antiviral immunity by deubiquitinates SQSTM1/p62 and promotes IRF3 degradation [232]."
36653801
reach
"Moreover, OTUD7B negatively regulates antiviral immunity by deubiquitinating p62, promoting IRF3 autophagic degradation and balancing type I interferon signaling during viral infection [16]."
40158182
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"With respect to viral infection, in vitro studies revealed that OTUD7b impairs innate anti-viral immunity in macrophages by deubiquitinating SQSTM1/p62 during vesicular stomatitis virus infection [58]."
37516734
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"For example, the cell growth-regulating nucleolar protein LYAR suppresses IFN production by targeting phosphorylated IRF3 [13], OTUD7B deubiquitinates SQSTM1/p62 and promotes IRF3 degradation to inhibit antiviral immunity [14], and the prolyl isomerase PIN1 negatively regulates the innate antiviral response by proteasome-dependent degradation of IRF3 [15]."
38516932
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"For example, the cell growth-regulating nucleolar protein LYAR suppresses IFN production by targeting phosphorylated IRF3 [13], OTUD7B deubiquitinates SQSTM1/p62 and promotes IRF3 degradation to inhibit antiviral immunity [14], and the prolyl isomerase PIN1 negatively regulates the innate antiviral response by proteasome-dependent degradation of IRF3 [15]."
38516932
reach
"OTUD7B deubiquitinates SQSTM1/p62 and promotes IRF3 degradation to regulate antiviral immunity."
35100065
reach
"OTUD7B deubiquitinates SQSTM1/p62 and promotes IRF3 degradation to regulate antiviral immunity."
35100065