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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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USP7 inhibits UHRF1. 3 / 7

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"However, active USP7 completely abolished the autoubiquitinylation of UHRF1 by removal of ubiquitin adducts."

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"Second, we hypothesize that HAUSP directly inhibits the E3 ubiquitin ligase activity of UHRF1."

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"USP7 prevents UHRF1 from autoubiquitinylation in vitro and regulates its stability in vivo."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

USP7 inhibits UHRF1. 3 / 7

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